Skip Navigation LinksHome > April 2008 - Volume 12 - Issue 2 > An Unusual Cause of Postmenopausal Bleeding
Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e3181571ae2
Case Reports

An Unusual Cause of Postmenopausal Bleeding

Wuntakal, Rekha MBBS, MD, DNB, MRCOG1; Janga, Deepa MD, MRCOG1; Satyanarayana, Durga MS, MRCOG2; Reynolds, Karina MD, FRCS, FRCOG2; Hollingworth, Antony MBChB, PhD, FRCS (Ed), FRCOG1

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Abstract

Background. Non-Hodgkin lymphoma usually presents with lymphadenopathy, fever, night sweats, and weight loss. Postmenopausal vaginal bleeding is a cardinal symptom of carcinoma of the endometrium or cervix but not one of non-Hodgkin lymphoma. Clinical awareness of this unusual mode of presentation is important.

Case. We report a case of non-Hodgkin lymphoma in a 60-year-old woman, who presented primarily with postmenopausal bleeding. Clinical examination revealed a "thickened" area on the posterior vaginal wall. Repeated vaginal biopsies showed fibrosis and inflammatory tissue only. Immunohistochemistry revealed non-Hodgkin lymphoma. This case highlights the diagnostic challenges such a complex case presents.

Conclusion. This case not only represents a case of non-Hodgkin lymphoma with genital involvement but also highlights the importance of diagnosis and management of such complex cases.

©2008The American Society for Colposcopy and Cervical Pathology

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