Objective. To provide consensus guidelines for the management of women with histologically confirmed cervical intraepithelial neoplasia (CIN), which can act as a precursor to invasive cervical cancer and represents one of the most common significant gynecologic diseases of women of reproductive age.
Participants. An independent panel of 121 experts in various aspects of the diagnosis and management of cervical cancer precursors, including representatives from 29 participating professional organizations, federal agencies, national and international health organizations, and others invited by the American Society for Colposcopy and Cervical Pathology (ASCCP).
Consensus Process. Guidelines for the management of women with CIN were developed through a multistep process. Working groups, who performed formal literature reviews and obtained input from the professional community at large by way of an interactive Internet-based bulletin board, developed draft management guidelines. At the ASCCP Consensus Conference, September 6–8, 2001, in Bethesda, Maryland, all guidelines were discussed, revised, and adopted by formal vote.
Conclusions. Evidence-based guidelines have been developed for the management of women with biopsy-confirmed CIN.
1Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, NY; 2Student Health Services, University of California–Santa Barbara, Santa Barbara, CA; 3American Social Health Association, Durham, NC; 4Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL; 5Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, Washington, DC; 6Institute of Women's Health, University of Miami, Miami, FL; and 7Department of Pathology, University of Florida, Gainesville, FL
Reprinted from the AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY, Vol. 189, Thomas C. Wright, Jr, MD, J. Thomas Cox, MD, L. Stewart Massad, MD, Jay Carlson, DO, Leo B. Twiggs, MD, and Edward J. Wilkinson, MD, “2001 Consensus Guidelines for the Management of Women with Cervical Intraepithelial Neoplasia”, Pages 295–304, Copyright 2003, with permission from Elsevier.
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