Hypertension-24 h ABPM center, 3rd Department of Medicine, Aristotle University, Thessaloniki, Greece
Objectives: To study blood pressure differences in ambulatory BP monitoring parameters that may associate with family history of hypertension in children and adolescence.
Methods: The study population consisted of 110 consecutive subjects who visited our hypertension center for evaluation of hypertension. All patients underwent 24 h ambulatory blood pressure (ABP) monitoring. Positive maternal and paternal history of hypertension was recorded in all subjects. Subjects were divided in four groups, those who had no history, subjects with maternal history or paternal history and finally subjects with history of hypertension in both parents.
Results: The age range of the study population was 3 to 20 years (13.26 ± 4.5 years). Average 24 h systolic blood pressure was 117.5 ± 11.7 mmHg, average 24 h diastolic BP was 66.4 ± 7.8 mmHg, and 24 h pulse pressure was 51.1 ± 8.6 mmHg.
Subjects with maternal history of hypertension had significantly higher average 24 h systolic BP compared to subjects with no history of parental hypertension (mean difference 7.95 with 95% confidence intervals 0.77 to 15.13 mmHg, Post Hoc Tukey's analysis). No statistically significant differences were found between the other groups.
Conclusions: Offspring with maternal family history of hypertension had higher 24 h systolic BP levels suggesting a possible maternal factor for the emerge of high blood pressure.