Ivth Medical Clinic of the University of Medicine and Pharmacy Victor Babes, Timisoara, Romania
Objective: Chronic kidney disease (CKD) is frequent in elderly patients and is also very difficult to diagnose because in elderly it is often asymptomatic. One of the most common findings in patients with CKD is a high blood pressure. The aim of this study is to establish the relationship between hypertension and CKD in elderly patients.
Design and Methods: The study was carried out on a group of 1073 elderly hypertensive patients admitted, in a 2 years period, in the IVth Medical Clinic of the University of Medicine and Pharmacy “Victor Babes” Timisoara. The mean age of the patients was 78,5 ± 13,5 years. Of them 67% were women and 33% men. Blood pressure values, serum creatinine, lipids values, left ventricular hypertrophy (LVH), and the presence of smoking were observed in each patient. Estimated glomerular filtration rate (GFR) was calculated according to the 4 variable MDRD equation. CKD was defined as an estimated GFR lower than 60 ml/min/1,73 m2.
Results: In 24,3% of all patients CKD was present. Of them 87% were women. Dyslipidemia was present in 64,9% of all patients. In the patients with CKD, dyslipidemia was present in 88,9% of the patients. LVH was present in all patients with CKD. 12% of patients were smoking.
Conclusions: CKD is highly prevalent in hypertensive elderly patients and is a strong cardiovascular risk factor.