Journal of Hypertension

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Journal of Hypertension:
doi: 10.1097/HJH.0b013e328352c3c7

Should ambulatory blood pressure monitoring be mandatory for future studies in resistant hypertension: a perspective

Doumas, Michaela; Anyfanti, Panagiotab; Bakris, Georgec

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Recent technologic advances rekindled interventional management of resistant hypertension, either by carotid baroreceptor activation or renal sympathetic denervation. Interventional techniques result in impressive falls in office blood pressure (BP); however, ambulatory BP reductions are rather modest. This disparity between office and ambulatory BP reductions is observed with antihypertensive drugs, but at a much lower degree. Available explanations are not convincing, therefore, we propose that sympathetic overactivity may partially explain this divergence. Further studies are needed to prove or disprove our hypothesis.

© 2012 Lippincott Williams & Wilkins, Inc.


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