Acne is one of the most common dermatological conditions affecting millions of people worldwide. Although often considered a disease of young people, it is increasingly seen in adults, especially adult women. Acne can cause significant physical and psychological suffering, and yet, there is relatively little research into causes and treatments. Increasing importance is being attached to patient and public involvement in healthcare, and this imperative includes providing the opportunity to contribute to the research agenda. This article explains a process in which patients, the public, and healthcare professionals are working collaboratively to identify research priorities in the field of acne.