Skip Navigation LinksHome > January/February 2014 - Volume 6 - Issue 1 > Generalized Annular and Papulosquamous Eruption
Journal of the Dermatology Nurses' Association:
doi: 10.1097/JDN.0000000000000018
Feature Articles

Generalized Annular and Papulosquamous Eruption

Sood, Apra; Khetarpal, Shilpi; Billings, Steven D.; Piliang, Melissa

Collapse Box


ABSTRACT: A 72-year-old man presented with a 2-year history of an asymptomatic rash on the trunk and upper extremities that progressed over 3 months and is aggravated by sunlight. There was no associated fever, joint pain, weight loss, shortness of breath, or malaise. His medications included atenolol, simvastatin, triamterene-hydrochlorothiazide, aspirin, fenofibrate, gemfibrozil, and ranitidine, all of which have been unchanged for years. He had a generalized eruption on the chest, back, and arms that included erythematous scaly papules and plaques; some of the plaques are annular and serpiginous. A skin biopsy shows a vacuolar interface dermatitis with apoptotic keratinocytes, increased mucin in the dermis, and a superficial and mid-dermal chronic inflammatory infiltrate. Laboratories included a complete blood count, complete metabolic panel, and antinuclear antibodies, all of which were normal. Direct immunofluorescence showed positive deposition of immunoglobulin IgE and C3 in a linear pattern at the dermal–epidermal junction. The triamterene-hydrochlorothiazide was discontinued, and the eruption cleared completely over the next 6 weeks with topical fluocinonide ointment twice daily.

Copyright © 2014 by the Dermatology Nurses' Association.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.