ABSTRACT: Although healthcare systems differ in the United Kingdom and United States, the fundamental principles of nursing, to care for and support patients, transcend geography. First-level nurses in the United Kingdom may undertake additional training to become nonmedical prescribers. Psoriasis is a chronic condition affecting around 3% of the U.K. population. Treatments available are topical, phototherapy, or systemic treatments. Topical treatments vary in efficacy, and patients require education and support to self-manage effectively. Nurse prescribers are in a position to provide nursing care and understanding as well as prescribe treatments to support patients in choices and treatments for their skin. This is illustrated in a case study.