Keloids are found at the site of tissue injury. They are easily identified but not easily remedied. In this case study, the author presents two patients with keloids: one whose keloids involved her ear lobes, the other with acne keloidalis. Both patients underwent several months of treatment, with slow improvement. Keloids are often recalcitrant to treatment and are prone to recurrence. Several new therapeutic treatment strategies are being studied and developed. I hope that through continued research, new techniques will be discovered to prevent and treat these benign but potentially cosmetically devastating growths.