Journal of Craniofacial Surgery

Skip Navigation LinksHome > September 2013 - Volume 24 - Issue 5 > Autologous Fat Graft in Scar Treatment
Journal of Craniofacial Surgery:
doi: 10.1097/SCS.0b013e3182a24548
Original Articles

Autologous Fat Graft in Scar Treatment

Klinger, Marco MD*; Caviggioli, Fabio MD; Klinger, Francesco Maria MD; Giannasi, Silvia MD*; Bandi, Valeria MD*; Banzatti, Barbara MD*; Forcellini, Davide MD*; Maione, Luca MD*; Catania, Barbara MD*; Vinci, Valeriano MD

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Introduction: Regenerative medicine is an emerging and rapidly evolving field of research and therapy, thanks to new discoveries on stem cells. Adipose tissue is a connective tissue which contains a reserve of mesenchymal stem cells. Clinical improvements in trophic characteristics of teguments after autologous fat graft are well described in literature. In this paper, we present our observation after 6 years of autologous fat graft experience in scar remodeling.

Materials and Methods: All patients recruited had retractile and painful scars compromising the normal daily activity/mobility of the joint involved. We performed surgical procedure with Coleman technique. In 20 patients, we performed a clinical assessment using Patient and Observer Scar Assessment Scale (POSAS) and Durometer measurements.

Results: In all treated scars, a qualitative improvement was shown both from an aesthetic and functional point of view. Most importantly, reduction or complete resolution of pain and increases in scar elasticity were objectively assessable in all cases. In patients studied using Durometer and POSAS score, areas treated with autologous fat graft showed statistically significant reduction in hardness measurements in comparison with areas infiltrated with saline solution. POSAS scores showed a statistically significant reduction of a great deal of POSAS parameters as a result of an improvement of both clinical evaluation and patient perception.

Conclusions: Injection of processed autologous fat seems to be a promising and effective therapeutic approach for scars with different origin such as burns and other trauma scars, and post-surgery and radiotherapy outcomes. In general, we can affirm that treated areas regain characteristics similar to normal skin, which are clinically objectivable, leading not only to aesthetic but also functional results.

© 2013 by Mutaz B. Habal, MD.

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