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Interstitial Growth of Bone Revisited

Sarnat, Bernard G. MD, DDS

Journal of Craniofacial Surgery:
Scientific Foundations

The distance between two or more metallic implants placed within the same flat bones (mandible, nasal, frontal, hyoplastron, hypoplastron) of young pigs, rabbits, and turtles followed by means of serial radiographs, remained the same for periods as long as 546 days. Thus, it is concluded that there is no interstitial growth. In 1743, Duhamel demonstrated that long bones grow at their ends and that there is no interstitial growth. This report is unique in that it demonstrates by use of radiopaque implants and serial radiographs that there is no interstitial growth of flat bones, which grow by apposition and resorption, and not endochondrally, such as occurs in long bones.

Author Information

Los Angeles, California

From the Section of Oral Biology, School of Dentistry and Division of Plastic Surgery, School of Medicine, University of California and Division of Plastic Surgery, Cedars-Sinai Medical Center, Los Angeles, California.

Address correspondence to Dr. Bernard G. Sarnat, 1875 Kelton Avenue, Los Angeles, CA 90025; e-mail:

© 2004 Mutaz B. Habal, MD