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Successful Treatment of Digital Tip Necrosis in Rheumatoid Vasculitis With Anti-CD20 Antibody Rituximab

Korkosz, Mariusz MD, PhD*; Królczyk, Jarosław MD; Telesińska-Jasiówka, Dorota MD*; Grodzicki, Tomasz MD, PhD

JCR: Journal of Clinical Rheumatology: January 2013 - Volume 19 - Issue 1 - p 43–45
doi: 10.1097/RHU.0b013e318277a092
Case Reports

Abstract: We report a successful treatment with rituximab in the case of rheumatoid vasculitis causing digital tips necrosis in exacerbated rheumatoid arthritis. The vasculitis lesions did not respond completely to intravenous methylprednisolone and cyclophosphamide but responded on rituximab treatment. Deep necrosis of a digital tip resolved entirely after completing a course of rituximab.

From the *Division of Rheumatology, Departments of Internal Medicine and Gerontology, and †Internal Medicine and Gerontology, College of Medicine, Jagiellonian University, Krakow, Poland.

M.K. has received lectures honoraria from Roche and Pfizer. T.G. has received lecture honoraria from Pfizer. For the remaining authors, none were declared.

The authors declare no conflict of interest.

Correspondence: Mariusz Korkosz, MD, PhD, Division of Rheumatology, Department of Internal Medicine and Gerontology, College of Medicine, Jagiellonian University, 10 Sniadeckich St 31-531 Krakow, Poland. E-mail: mariusz.korkosz@mp.pl.

© 2013 Lippincott Williams & Wilkins, Inc.