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Journal of Clinical Gastroenterology:
doi: 10.1097/MCG.0b013e3181a7ed2a
ONLINE ARTICLES: Original Articles

Findings on Serial Surveillance Colonoscopy in Patients With Low-risk Polyps on Initial Colonoscopy

Miller, Jocelyne MD, MSCE*; Mehta, Neil MD; Feldman, Michael MD; Furth, Emma MD; Ginsberg, Gregory G. MD*; Yang, Yu-Xiao MD, MSCE*; Lewis, James D. MD, MSCE*

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Abstract

Goals: This study describes the prevalence of adenomatous polyps at serial follow-up exams after a colonoscopy finding 1 to 2 small tubular adenomas.

Study: We conducted a retrospective cohort of patients with 1 to 2 small tubular adenomas on an initial colonoscopy who underwent at least 2 additional surveillance examinations. Our primary outcome was any or advanced adenomas on the third colonoscopy.

Results: Eighty-eight patients met inclusion criteria. At the second and third colonoscopy, 31/88 (35.2%) patients and 26/88 (29.6%) patients had at least 1 adenoma, respectively. Among the 28 patients with 1 to 2 small tubular adenomas on colonoscopy no. 2, the prevalence of any adenomas on colonoscopy no. 3 was 39.3% [95% confidence interval (CI): 21.5%-59.4%]. Among the 56 patients without adenomas at colonoscopy no. 2, the prevalence of any and advanced adenomas on colonoscopy no. 3 was 25% (95% CI: 14.4%-38.4%), and 3.6% (95% CI: 0.4%-12.3%), respectively.

Conclusions: In patients with 1-2 small tubular adenomas on initial colonoscopy the prevalence of adenomas and advanced lesions on the third colonoscopy remains high even if no adenomas are found on the second colonoscopy.

© 2010 Lippincott Williams & Wilkins, Inc.

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