Skip Navigation LinksHome > January 2010 - Volume 44 - Issue 1 > Celiac Disease: Prevention and Treatment
Journal of Clinical Gastroenterology:
doi: 10.1097/MCG.0b013e3181b7ead2
ALIMENTARY TRACT: Clinical Review

Celiac Disease: Prevention and Treatment

Selimoğlu, Mukadder Ayşe MD; Karabiber, Hamza MD

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Abstract

Celiac disease is a common multisystemic disorder that may be diagnosed at any age. Owing to the increasing prevalence, prevention strategies, including encouragement of breastfeeding and introduction of small amounts of gluten whereas still on breastfeeding at fourth to sixth month of age, become more important than before. For avoiding complications of celiac disease, a strict gluten-free diet is essential. A lifelong gluten-free diet may bring about difficulties as avoiding gluten completely is problematic owing to the contamination with gluten of presumably gluten free foods. New therapeutic approaches include enzyme supplementation, correction of the intestinal barrier defect against gluten entry, blocking of gliadin presentation by human leukocyte antigen blockers and tissue transglutaminase inhibitors.

© 2010 Lippincott Williams & Wilkins, Inc.

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