Skip Navigation LinksHome > November/December 2004 - Volume 38 - Issue 10 > Magnetic Resonance Cholangiopancreatography in Obstructive J...
Journal of Clinical Gastroenterology:
Liver, Pancreas and Biliary Tract: Clinical Research

Magnetic Resonance Cholangiopancreatography in Obstructive Jaundice

Vaishali, M. D. MD*; Agarwal, A. K. MD*; Upadhyaya, D. N. MS†; Chauhan, V. S. MBBS†; Sharma, O. P. MD*; Shukla, V. K. MCh†

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Goals: To determine the ability of magnetic resonance cholangiopancreatography (MRCP) to diagnose the level and cause of obstruction in patients with obstructive jaundice.

Background: The limitations of available imaging modalities have led to the increasing use of MRCP, which is a noninvasive and highly accurate technique in evaluating patients with biliary obstruction.

Study: Thirty patients were included in this study. MRCP was done using a fat suppressed, heavily T2 weighted fast spin echo sequence. The MRCP findings were confirmed on surgical exploration or clinical follow-up.

Results: MRCP could correctly identify ductal dilatation and the level of obstruction in all cases, except one. All causes of obstruction, except three, were detected. It failed to detect a common bile duct calculus in a minimally dilated ductal system and misdiagnosed a case of focal chronic pancreatitis as carcinoma head pancreas and a small pancreatic head mass as cholangiocarcinoma. It had a sensitivity of 94.44%, specificity of 81.81%, positive predictive value of 89.47%, and negative predictive value of 90% for the detection of malignant causes. The overall diagnostic accuracy for detection of level and cause of obstruction was 96.3% and 89.65%, respectively.

Conclusion: The high diagnostic accuracy of MRCP in evaluating patients with obstructive jaundice indicates that it has the potential to become the diagnostic modality of choice in such patients.

© 2004 Lippincott Williams & Wilkins, Inc.


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