Skip Navigation LinksHome > April 2001 - Volume 32 - Issue 4 > Spontaneous Fungal Peritonitis (Candida glabrata) in a Patie...
Journal of Clinical Gastroenterology:
Case Reports

Spontaneous Fungal Peritonitis (Candida glabrata) in a Patient with Cirrhosis

Nair, Satheesh M.D.; Kumar, K. Shiva M.D.; Sachan, Pavan M.D.; Corpuz, Marilou M.D.

Collapse Box


We report a case of spontaneous fungal peritonitis in a patient with cirrhosis. A 70-year-old woman with cirrhosis secondary to autoimmune hepatitis was admitted with fever and abdominal distention. Paracentesis revealed neutrocytosis, and despite appropriate antibacterial coverage, no clinical improvement was noted and the ascitic fluid white cell count increased on repeat paracentesis. Two consecutive ascitic fluid cultures grew Candida glabrata, and antifungal therapy with amphotericin was initiated, pending sensitivity of the isolate. Because of worsening renal function, amphotericin was discontinued and itraconazole was started, as sensitivity of the isolate was then available. Antifungal therapy resulted in resolution of ascitic fluid neutrocytosis and culture negativity. However, the patient's renal function continued to deteriorate, necessitating hemodialysis. Despite multiple courses of antibiotics, she died of fulminant sepsis and multiorgan failure.

© 2001 Lippincott Williams & Wilkins, Inc.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.