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Antiphospholipid Syndrome Presenting as Portopulmonary Hypertension

Bayraktar, Yusuf M.D.; Tanaci, Nedret M.D.; Egesel, Türker M.D.; Gököz, Aytaç M.D.; Balkanci, Ferhun M.D.

Journal of Clinical Gastroenterology: April 2001 - Volume 32 - Issue 4 - pp 359-361
Case Reports

The association of pulmonary hypertension with portal hypertension, also called portopulmonary hypertension, is a well-described condition. The pathogenesis of this association remains unclear. We describe a 34-year-old female patient with “primary antiphospholipid syndrome” and portopulmonary hypertension. Our finding supports that in situ microthrombosis associated with the presence of anticardiolipin antibodies could be the pathophysiologic explanation for both portal and pulmonary hypertension.

From the Departments of Radiology (F.B.), Pathology (A.G.), and Internal Medicine (N.T.), and the Section of Gastroenterology (Y.B., T.E.), School of Medicine, Hacettepe University, Ankara, Turkey.

Submitted July 27, 1999.

Accepted February 25, 2000.

Address correspondence and reprint requests to Dr. Yusuf Bayraktar, Güniz Sokak No: 29/11, Kavaklidere 06700, Ankara, Turkey.

© 2001 Lippincott Williams & Wilkins, Inc.