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Malignant Renal Epithelioid Angiomyolipoma With Liver Metastasis After Resection: A Case Report With Multimodality Imaging and Review of the Literature

Vicens, Rafael A. MD; Jensen, Corey T. MD; Korivi, Brinda Rao MD, MPH; Bhosale, Priya R. MD

Journal of Computer Assisted Tomography: July/August 2014 - Volume 38 - Issue 4 - p 574–577
doi: 10.1097/RCT.0000000000000101
Abdominal Imaging

Renal epithelioid angiomyolipoma (EAML) is a perivascular epithelioid cell tumor. Although the overwhelming majority of renal EAMLs are benign, cases of aggressive behavior and malignancy have been reported. Here, we report the case of a 62-year-old woman with a 12.5-cm renal EAML, who underwent resection and developed a 10.5-cm hepatic EAML 15 months after the surgery. Although multicentric disease is a possibility, the temporal course is consistent with metastasis from the poorly differentiated primary tumor. This is the only report with multimodality imaging to detail new metastatic disease during surveillance after intended curative resection of an EAML.

From the Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX.

Received for publication March 19, 2014; accepted March 31, 2014.

Reprints: Corey T. Jensen, MD, Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler St, Unit 1473, Houston, TX 77030-4009 (e-mail: cjensen@mdanderson.org).

An expanded discussion of this “Case of the Quarter” can be found at the SCBT-MR Web site: scbtmr.dnnstaging.com

The authors declare no conflict of interest.

© 2014 by Lippincott Williams & Wilkins