Skip Navigation LinksHome > July/August 2014 - Volume 38 - Issue 4 > Detection and Localization of Bile Duct Leaks After Cholecys...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0000000000000083
Abdominal Imaging

Detection and Localization of Bile Duct Leaks After Cholecystectomy Using Gd-EOB-DTPA—Enhanced MR Cholangiography: Retrospective Study of 16 Patients

Ratcliffe, Gregory E. MD*; Kirkpatrick, Iain D. MD; Anik Sahni, V. MD; Greenberg, Howard M. MD*; Henderson, Blair MD*; Radulovic, Dejana MD§; Mottola, Jeffrey C. MD*

Collapse Box


Objective: To determine if gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) cholangiography can detect and localize bile duct leaks in postcholecystectomy patients.

Material and Methods: Four blinded independent radiologists performed a retrospective review of 16 consecutive patients who underwent MR cholangiography with intravenous Gd-EOB-DTPA for the evaluation of possible biliary leak. Image quality, ductal opacification, and presence and location of any bile leak were evaluated. An independent observer determined the criterion standard using a consensus of all chart, clinical, and imaging findings.

Results: All 6 bile leaks confirmed at endoscopic retrograde cholangiopancreatography were diagnosed by all reviewers (sensitivity, 100%). Of the 10 patients with no leak, only one reader incorrectly diagnosed a bile leak in a single case (specificity, 98%). The accuracy for detection of the site of leak with Gd-EOB-DTPA-enhanced MR cholangiography was 80%.

Conclusion: Gadolinium-EOB-DTPA–enhanced MR can detect bile leaks with a high sensitivity and specificity.

© 2014 by Lippincott Williams & Wilkins



Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.