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Differentiation of Gastric True Leiomyoma From Gastric Stromal Tumor Based on Biphasic Contrast-Enhanced Computed Tomographic Findings

Zhu, Hui MD*; Chen, Haoyan MD; Zhang, Shengjian MD*; Peng, Weijun MD*

Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182ab0934
Abdominal Imaging

The objective of this study was to identify the computed tomographic criteria that differentiate gastric true leiomyoma from gastric stromal tumor.

Materials and Methods: Computed tomographic images of gastric true leiomyoma (n = 11) and gastric stromal tumor (n=30) were reviewed. The location, contour, growth pattern, enhancement pattern, necrosis, and ulceration were analyzed. Long diameter (LD), short diameter (SD), LD/SD ratio, and enhancement degree were measured and calculated. The Fisher exact test, grouped t test, rank sum test, and receiver operating characteristic curve were analyzed. Sensitivity and specificity were also calculated.

Results: Cardial location, round/ovoid contour, intraluminal growth, homogeneous enhancement, absence of necrosis, less than 3.35 cm in LD and less than 2.3 cm in SD, enhancement degree of less than 12.5 Hounsfield units in the arterial phase versus less than 31.5 Hounsfield units in the portal venous phase were found to be significant variables for differentiating gastric true leiomyoma from gastric stromal tumor (P < 0.05).

Conclusions: These 9 computed tomographic criteria are helpful to differentiate gastric true leiomyoma from gastric stromal tumor.

Author Information

From the *Department of Radiology, Fudan University Shanghai Cancer Center; and †Department of Gastroenterology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Diseases, Shanghai, China.

Received for publication August 18, 2013; accepted October 7, 2013.

Reprints: Weijun Peng, MD, Department of Radiology, Fudan University Shanghai Cancer Center, 270 DongAn Rd, Shanghai, 200032, China (e-mail:

The authors declare no conflict of interest.

© 2014 by Lippincott Williams & Wilkins