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Ultra-Low Contrast Computed Tomographic Angiography (CTA) With 20-mL Total Dose for Transcatheter Aortic Valve Implantation (TAVI) Planning

Azzalini, Lorenzo MD, MSc*†‡; Abbara, Suhny MD*; Ghoshhajra, Brian B. MD, MBA*

Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182a14358
Abdominal Imaging

Abstract: Transcatheter aortic valve implantation workup includes assessment of the aorta and the iliofemoral arteries by computed tomographic angiography. An important group of transcatheter aortic valve implantation candidates have severe renal failure. We tested a novel computed tomographic angiography protocol (128-detector–row dual-source scanner, high-pitch helical mode) with ultralow contrast volume (20 mL) in 8 patients, compared with 8 controls. Contrast-to-noise ratio and subjective image quality, albeit lower than in the controls, were suitable for interpretation in the ultralow contrast volume group throughout all measured locations.

Author Information

From the *Cardiac Imaging, Department of Radiology, and †Interventional Cardiology, Heart Center, Massachusetts General Hospital, Boston; and ‡Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.

Received for publication March 21, 2013; accepted June 18, 2013.

Reprints: Brian B. Ghoshhajra, MD, MBA, Clinical Cardiac CT and MRI, Cardiac MR PET CT Program, Massachusetts General Hospital, 55 Fruit St, GRB-295, Boston, MA 02114 (e-mail:

The authors report no conflict of interest.

© 2014 by Lippincott Williams & Wilkins