Skip Navigation LinksHome > January/February 2014 - Volume 38 - Issue 1 > In Vivo and Ex Vivo Magnetic Resonance Spectroscopy in the C...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182a9103a

In Vivo and Ex Vivo Magnetic Resonance Spectroscopy in the Characterization of Hemangioblastoma Cyst Fluid

Crisi, Girolamo MD*; Filice, Silvano MSc; Pertinhez, Thelma A. PhD; Ventura, Elisa MD§; Servadei, Franco MD

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Abstract: Peritumoral cyst formation is commonly associated with hemangioblastomas of the central nervous system. Results of a proteomic profiling of hemangioblastoma cyst fluid suggested that cyst formation, whether intratumoral or peritumoral, is a consequence of vascular leakage because protein profiles of cyst fluid and blood serum were similar. To the best of our knowledge, this is the first report of in vivo and ex vivo magnetic resonance spectroscopy analyses of hemangioblastoma cyst fluid that investigates on the mechanism leading to peritumoral cyst formation.

© 2014 by Lippincott Williams & Wilkins



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