You could be reading the full-text of this article now if you...

If you have access to this article through your institution,
you can view this article in

Correlations Between Tumor Stroma Characters and Dynamic Enhanced MDCT Findings in Nodular Pulmonary Adenocarcinoma

Wang, Yong MD*; Wang, Jin-an MD*; Liang, Kun-ru MD*; Liang, Ming-zhu MD; Liu, Xue-guo MD, PhD

Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182a38ad5
Thoracic Imaging
Abstract

Objective: This study aimed to evaluate correlations between tumor stroma characters and dynamic contrast-enhanced computed tomographic (CT) findings in nodular pulmonary adenocarcinoma.

Methods: Thirty-three patients with nodular pulmonary adenocarcinoma underwent dynamic contrast-enhancement CT scan before surgery. CT findings include wash-in, wash-out, and distribution of enhancement. The proportion of invasive and noninvasive stroma in tumor was calculated.

Results: Invasive and noninvasive stroma proportion in tumor was correlated positively with wash-in and wash-out enhancement, respectively.

Conclusions: Tumor stroma proliferation may explain the pathologic basis of CT dynamic enhancement and be a useful prognostic factor of pulmonary adenocarcinoma.

Author Information

From the *Department of Radiology, Zhongshan Hospital of Xiamen University, Xiamen, Fujian Province; and †Department of Radiology, The 5th Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guang Dong Province, China.

Received for publication May 9, 2013; accepted July 2, 2013.

Reprints: Xue-guo Liu, MD, PhD, Department of Radiology, The 5th Affiliated Hospital of Sun Yat-Sen University, 52 Mei Hua East Rd, Zhuhai 519000, Guang Dong Province, China (e-mail: liuxueg@mail.sysu.edu.cn).

The authors have no conflicts of interest to report.

© 2014 by Lippincott Williams & Wilkins