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Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182a38ad5
Thoracic Imaging

Correlations Between Tumor Stroma Characters and Dynamic Enhanced MDCT Findings in Nodular Pulmonary Adenocarcinoma

Wang, Yong MD*; Wang, Jin-an MD*; Liang, Kun-ru MD*; Liang, Ming-zhu MD; Liu, Xue-guo MD, PhD

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Abstract

Objective

This study aimed to evaluate correlations between tumor stroma characters and dynamic contrast-enhanced computed tomographic (CT) findings in nodular pulmonary adenocarcinoma.

Methods

Thirty-three patients with nodular pulmonary adenocarcinoma underwent dynamic contrast-enhancement CT scan before surgery. CT findings include wash-in, wash-out, and distribution of enhancement. The proportion of invasive and noninvasive stroma in tumor was calculated.

Results

Invasive and noninvasive stroma proportion in tumor was correlated positively with wash-in and wash-out enhancement, respectively.

Conclusions

Tumor stroma proliferation may explain the pathologic basis of CT dynamic enhancement and be a useful prognostic factor of pulmonary adenocarcinoma.

Copyright © 2014 by Lippincott Williams & Wilkins

  

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