Skip Navigation LinksHome > November/December 2013 - Volume 37 - Issue 6 > Physician Preference Between Low-Dose Computed Tomography Wi...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0000000000000024
Abdominal CT Techniques and Dose Optimization

Physician Preference Between Low-Dose Computed Tomography With a Sinogram-Affirmed Iterative Reconstruction Algorithm and Routine-Dose Computed Tomography With Filtered Back Projection in Abdominopelvic Imaging

Hardie, Andrew D. MD; Tipnis, Sameer V. PhD; Rieter, William J. MD, PhD; Rissing, Michael S. MD; De Cecco, Carlo N. MD

Collapse Box


Objective: The aim of this study was to directly compare the preference between low-dose sinogram-affirmed iterative reconstruction (SAFIRE) and routine filtered back projection (FBP) abdominopelvic computed tomography (CT).

Methods: A retrospective review identified 41 subjects who had undergone 2 different CT examinations at different times (a CT with reduced radiation dose SAFIRE and also a CT with routine-dose FBP). Radiation dose, patient size, and image noise were recorded. Two independent readers assessed the paired CT studies for preference in image quality in regard to 3 clinically relevant diagnostic endpoints (bowel pathology, biliary pathology, and general purpose).

Results: Radiation dose was significantly lower for SAFIRE (mean, 7.6 mGy; range, 4.1–15.4 mGy) than FBP (12.9 mGy; 6.7–31.6 mGy) (P < 0.001). Sinogram-affirmed iterative reconstruction was preferred for the general purpose and bowel evaluations, particularly when the level of radiation dose reduction was less than 33%. The preference for interpretation of the biliary system was equivocal, especially when the level of radiation reduction was increased greater than 33%. Filtered back projection was preferred when SAFIRE had a radiation reduction from FBP of greater than 50%.

Conclusions: For abdominopelvic CT, low-dose CT with SAFIRE may produce preferred image quality over FBP up to levels of 50% dose reduction.

© 2013 by Lippincott Williams & Wilkins



Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.