Skip Navigation LinksHome > July/August 2013 - Volume 37 - Issue 4 > Three-Phase Parathyroid 4-Dimensional Computed Tomography In...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e31828beb34

Three-Phase Parathyroid 4-Dimensional Computed Tomography Initial Experience: Inexperienced Readers Have High Accuracy and High Interobserver Agreement

Sepahdari, Ali R. MD*; Yeh, Michael W. MD; Rodrigues, David MD; Khan, Sarah N. MD*; Harari, Avital MD

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Objective: Multiphase multidetector contrast-enhanced parathyroid CT (4-dimensional computed tomography [4D-CT]) is an emerging tool for evaluating patients with primary hyperparathyroidism. Our goal was to describe the initial performance of 2 inexperienced readers in interpretation of 4D-CT.

Methods: Twenty-three subjects who received 4D-CT and successful surgical exploration were studied (14 initial and 9 repeat explorations; 15 single-gland disease and 8 multigland disease) A staff neuroradiologist prospectively interpreted all studies, and a neuroradiology fellow retrospectively interpreted all studies; their results were compared with the surgical findings for each side of the neck separately.

Results: The prospective readings were 78% accurate overall, 97% accurate in the subset of single-gland disease cases, and 89% accurate in re-exploration cases. There was 91% concordance in interpretation between observers, with κ of 0.83.

Conclusions: Initial results after implementation of 4D-CT show high accuracy of interpretation for inexperienced observers, comparable to published data, and high interobserver agreement.

© 2013 by Lippincott Williams & Wilkins



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