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Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e31828b683b
Abdominal Imaging

Discrepancy Between Preoperative Imaging and Surgical Findings in Patients With Advanced Ovarian Cancer: A Study of Initial False-Negative Lesions

Ko, Seok Min MD*; Jung, Dae Chul MD*; Oh, Young Taik MD*; Kim, Sun Ho MD; Kang, Sokbom MD

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Objective: The objective of this study was to determine the patterns of erroneous interpretation of preoperative computed tomography (CT) for detection of peritoneal lesions in advanced ovarian cancer.

Methods: Between 2007 and 2011, 148 patients with International Federation of Gynecology and Obstetrics stage IIIC-IV ovarian cancer, who underwent multi–detector-row CT before primary cytoreduction, were enrolled. We reviewed the preoperative CT and compared the findings with the surgical findings. For the discrepant cases, false-negative cases were reevaluated after revealing of surgical findings and were categorized as either absence or presence of lesion (missed case). We performed region-based comparisons according to predefined peritoneal lesion locations.

Results: Sixty-eight false-negative cases were identified, of which 43 were revealed to be initially missed cases. The most common locations were found to be the small-bowel mesentery (21%), subdiaphragmatic space (19%), and porta hepatis (16%).

Conclusions: The missed peritoneal implants commonly resided in the same sites of preoperative imaging criteria that could predict suboptimal primary cytoreduction.

© 2013 by Lippincott Williams & Wilkins



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