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Quantitative and Qualitative Comparison of Standard-Dose and Low-Dose Pediatric Head Computed Tomography: A Retrospective Study Assessing the Effect of Adaptive Statistical Iterative Reconstruction

Kilic, Koray MD; Erbas, Gonca MD; Guryildirim, Melike MD; Konus, Oznur Leman MD; Arac, Mehmet MD; Ilgit, Erhan MD; Isik, Sedat MD

Journal of Computer Assisted Tomography: May/June 2013 - Volume 37 - Issue 3 - p 377–381
doi: 10.1097/RCT.0b013e31828426de
Pediatric Radiology

Objectives: Our aim was to assess the effect of adaptive statistical iterative reconstruction (ASIR) on pediatric head computed tomography (CT) examinations.

Methods: We retrospectively reviewed 305 pediatric head CT examinations. The study population consisted of standard dose (STD, n = 152) examinations reconstructed with filtered back projection and low dose (LD, n = 153) examinations reconstructed with 30% (LD30) and 0% (LD0) ASIR. We compared groups by means of radiation dose, noise measures, and visual grading. Student t test, 1-way analysis of variance test, and Mann-Whitney U test were used for statistical analysis.

Results: The dose in the LD30 group was significantly lower (29%) than that in the STD group (P < 0.001). The noise in the white matter (P < 0.001), SNR (P < 0.001), and subjective image noise (P = 0.044) was significantly better in the STD group than those in the LD30 group. There was no significant difference between LD30 and STD groups in the sharpness (P = 0.141), diagnostic acceptability (P = 0.079), and artifacts (P = 0.750) and contrast-to-noise ratio (P = 0.718).

Conclusions: In conclusion, we found that a blend of 30% ASIR in a 16-slice multidetector CT produces diagnostically acceptable pediatric head CT examinations with a 29% less dose.

From the Department of Radiology, Gazi University School of Medicine, Ankara, Turkey.

Received for publication September 12, 2012; accepted December 19, 2012.

Reprints: Koray Kilic, MD, Department of Radiology, Gazi University School of Medicine, 06510 Besevler, Ankara, Turkey (e-mail:

This study was presented as an electronic poster (poster no. C-1001) at the European Congress of Radiology held in Vienna, Austria, 2012.

The authors have no actual or potential conflict of interest in relation to this article.

© 2013 by Lippincott Williams & Wilkins