Skip Navigation LinksHome > May/June 2013 - Volume 37 - Issue 3 > Multiphase Multi–Detector Row Computed Tomography in the Set...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182838680
Cardiovascular Imaging

Multiphase Multi–Detector Row Computed Tomography in the Setting of Chronic Liver Disease and Orthotopic Liver Transplantation: Can a Series Be Eliminated in Order to Reduce Radiation Dose?

Luke, Frank E. MD*†; Allen, Brian C. MD*‡; Moshiri, Sara T. MD; Ho, Lisa M. MD*; Massey, Christopher M. MD*∥; Stinnett, Sandra S. Dr PH; Muir, Andrew J. MD#; Jaffe, Tracy A. MD*

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Abstract

Objective

The objectives of this study were to explore utilization of multi–detector row computed tomography (MDCT) in screening for hepatocellular carcinoma (HCC) and to modify a liver CT protocol with a goal of dose reduction.

Methods

An electronic mail survey querying HCC surveillance practices was sent. One hundred forty consecutive patients referred for HCC indications underwent 4-phase MDCT of the liver. The unenhanced and delayed phases were evaluated by 3 readers for identification of HCC and reader confidence. The estimated effective dose (ED) was calculated.

Results

Computed tomography is primarily used to screen for HCC. Average estimated ED was 35.5 mSv. Unenhanced phase did not add to reader confidence; delayed phase increased confidence in 47% of cases. Thirty-two percent of the screening population had cumulative ED of greater than 200 mSv.

Conclusions

Multi–detector row CT of the liver is used frequently in screening for HCC. Unenhanced phase imaging does not add to HCC detection and may be eliminated to reduce radiation dose.

Copyright © 2013 by Lippincott Williams & Wilkins

  

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