Skip Navigation LinksHome > May/June 2013 - Volume 37 - Issue 3 > Multiphase Multi–Detector Row Computed Tomography in the Set...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182838680
Cardiovascular Imaging

Multiphase Multi–Detector Row Computed Tomography in the Setting of Chronic Liver Disease and Orthotopic Liver Transplantation: Can a Series Be Eliminated in Order to Reduce Radiation Dose?

Luke, Frank E. MD*†; Allen, Brian C. MD*‡; Moshiri, Sara T. MD; Ho, Lisa M. MD*; Massey, Christopher M. MD*∥; Stinnett, Sandra S. Dr PH; Muir, Andrew J. MD#; Jaffe, Tracy A. MD*

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Objective: The objectives of this study were to explore utilization of multi–detector row computed tomography (MDCT) in screening for hepatocellular carcinoma (HCC) and to modify a liver CT protocol with a goal of dose reduction.

Methods: An electronic mail survey querying HCC surveillance practices was sent. One hundred forty consecutive patients referred for HCC indications underwent 4-phase MDCT of the liver. The unenhanced and delayed phases were evaluated by 3 readers for identification of HCC and reader confidence. The estimated effective dose (ED) was calculated.

Results: Computed tomography is primarily used to screen for HCC. Average estimated ED was 35.5 mSv. Unenhanced phase did not add to reader confidence; delayed phase increased confidence in 47% of cases. Thirty-two percent of the screening population had cumulative ED of greater than 200 mSv.

Conclusions: Multi–detector row CT of the liver is used frequently in screening for HCC. Unenhanced phase imaging does not add to HCC detection and may be eliminated to reduce radiation dose.

© 2013 by Lippincott Williams & Wilkins



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