Skip Navigation LinksHome > January/February 2013 - Volume 37 - Issue 1 > Detection of Brain Metastases by 3-Dimensional Magnetic Reso...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e318271f216
Neuroradiology

Detection of Brain Metastases by 3-Dimensional Magnetic Resonance Imaging at 3 T: Comparison Between T1-Weighted Volume Isotropic Turbo Spin Echo Acquisition and 3-Dimensional T1-Weighted Fluid-Attenuated Inversion Recovery Imaging

Yoshida, Atsushi MD; Tha, Khin Khin MD, PhD; Fujima, Noriyuki MD, PhD; Zaitsu, Yuri MD, PhD; Yoshida, Daisuke MD; Tsukahara, Akiko MD; Onodera, Shunsuke MD, PhD; Shirato, Hiroki MD, PhD; Terae, Satoshi MD, PhD

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Abstract

Objective: This study aimed to compare the diagnostic performance in the detection of brain metastases between contrast-enhanced T1-weighted volume isotropic turbo spin echo acquisition (T1-VISTA) and 3-dimensional T1-weighted fluid-attenuated inversion recovery (3D-T1-FLAIR) imaging at 3 T.

Methods: Two neuroradiologists selected 129 true (metastases) and 70 false (vessels and artifacts) lesions on the contrast-enhanced T1-VISTA and 3D-T1-FLAIR images of 14 cancer patients with hyperintense brain lesions. Four blinded neuroradiologists distinguished between the true and false lesions, using a 5-point confidence rating scale. The receiver operating characteristic analysis was performed to compare the diagnostic performance. Contrast-to-noise ratio of the true lesions was also compared between the 2 sequences by using paired t tests.

Results: For lesions less than 3 mm, the area under curve and sensitivity achieved by T1-VISTA imaging were significantly greater than 3D-T1-FLAIR imaging. The contrast-to-noise ratio was also significantly greater with T1-VISTA imaging.

Conclusions: The contrast-enhanced T1-VISTA imaging is better suited than 3D-T1-FLAIR imaging, for detection of small metastases.

© 2013 Lippincott Williams & Wilkins, Inc.

  

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