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Non–Contrast-Enhanced Magnetic Resonance Angiography Using T2-Weighted 3-Dimensional Fat-Suppressed Turbo Spin Echo (SPACE): Diagnostic Performance and Comparison With Contrast-Enhanced Magnetic Resonance Angiography Using Volume Interpolated Breath-Hold Examination in the Detection of Portosystemic and Portohepatic Collaterals

Song, Qiong MD*†; Zeng, Mengsu PhD, MD*; Chen, Caizhong BS*; Ma, Jing MD*; Yun, Hong MD*; Rao, Shengxiang PhD, MD*; Yao, Xiuzhong PhD, MD*

Journal of Computer Assisted Tomography: November/December 2012 - Volume 36 - Issue 6 - p 675–680
doi: 10.1097/RCT.0b013e31826999df
Cardiothoracic Imaging

Objectives: The objective of this study was to evaluate the diagnostic performance of non–contrast-enhanced magnetic resonance angiography (non–CE-MRA) using SPACE (“Sampling Perfection with Application optimized Contrasts using different flip angle Evolutions”) in comparison with CE-MRA using volume interpolated breath-hold examination (VIBE) in the detection of portosystemic and portohepatic collaterals.

Methods: Thirty consecutively enrolled cirrhotic patients with suspicion of portosystemic and portohepatic collaterals underwent SPACE followed by VIBE at 1.5-T magnetic resonance imaging scanner. The contrast-to-noise ratio, signal-to-noise ratio, and scores of the portal vein segments and overall image were used to compare the diagnostic performance of SPACE with that of VIBE. The paired Student t test and the Wilcoxon signed rank test were used for statistical analysis.

Results: Diagnostic results of SPACE were equivalent to those of VIBE. However, both the signal-to-noise ratio and contrast-to-noise ratio of portal vein segments in the former were better than those in the latter (P < 0.0001), and the scores of displaying the portal vein distal branches in SPACE were higher than those in VIBE (P < 0.05).

Conclusions: The SPACE has a comparable ability in demonstrating portosystemic and portohepatic collaterals as well as VIBE does.

From the *Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai; and †Department of Radiology, Zhejiang Provincial People’s Hospital, Hangzhou, People’s Republic of China.

Received for publication May 8, 2012; accepted July 11, 2012.

Reprints: Mengsu Zeng, PhD, MD, Department of Radiology, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai, People’s Republic of China 200032 (e-mail:

The authors have no conflicts of interest to declare.

© 2012 Lippincott Williams & Wilkins, Inc.