Skip Navigation LinksHome > November/December 2012 - Volume 36 - Issue 6 > Comparison of 320-Row Computed Tomography Coronary Angiograp...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e31826ab24a
Cardiothoracic Imaging

Comparison of 320-Row Computed Tomography Coronary Angiography With Conventional Angiography for the Assessment of Coronary Artery Disease With Different Atherosclerotic Plaque Characteristics

Yang, Qing-Hui MD; Chen, Yan-Jun MD; Liu, Qian-Qian MD; Dong, Min MD; Wen, Liang MD; Song, Xiang MD; Lv, Yan-Jie MD; Gong, Ying-Zi MD; Li, Xue-Qi MD

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Objective: The objective of this study was to compare the accuracy of 320-row computed tomography angiography (CTA) with conventional coronary angiography.

Methods: Two hundred seventy-four patients with coronary artery disease who received both invasive coronary angiography and 320-row CTA were included. Stenosis of 50% or greater was considered obstructive.

Results: In patient-based analysis, accuracy of CTA was 89.4%, with sensitivity of 94.6% and specificity of 54.3%. In segment-based analysis, the overall (4110 segments) accuracy of CTA was 90.7%, with sensitivity of 66.5% and specificity of 95.8%. For the segments with plaques (1191 segments), accuracy of CTA was 80.1%, with sensitivity of 83.5% and specificity of 77.0%. For segments with no plaque (2919 segments), accuracy of CTA was 95.0%, with sensitivity of 0.7% and specificity of 100.0%. For the segments with stents (110 segments), the accuracy of CTA was 86.4%.

Conclusions: A 320-row CTA has potential to detect coronary lesions with soft and intermediate plaques.

© 2012 Lippincott Williams & Wilkins, Inc.



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