Skip Navigation LinksHome > September/October 2012 - Volume 36 - Issue 5 > Validation of Dual-Source Single-Tube Reconstruction as a Me...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e318263cc1b
Abdominal Imaging

Validation of Dual-Source Single-Tube Reconstruction as a Method to Obtain Half-Dose Images to Evaluate Radiation Dose and Noise Reduction: Phantom and Human Assessment Using CT Colonography and Sinogram-Affirmed Iterative Reconstruction (SAFIRE)

Fletcher, Joel G. MD*; Grant, Katharine L.R. PhD; Fidler, Jeff L. MD*; Shiung, Maria BA*; Yu, Lifeng PhD*; Wang, Jia PhD; Schmidt, Bernhard PhD; Allmendinger, Thomas PhD; McCollough, Cynthia H. PhD*

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Objective: To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT.

Methods: Phantoms of varying sizes were scanned at multiple tube potentials using dose-matched dual-source (DS) and single-source (SS) protocols. Images from single-tube reconstruction of DS data were compared with SS images acquired at half-original CTDIvol. Thirty patients underwent supine SS and dose-matched prone DS CT colonography (CTC). Half-dose prone images were reconstructed with sinogram-affirmed iterative reconstruction (SAFIRE). Two radiologists scored image quality on 2-dimensional (2D) and 3D images.

Results: Image noise was similar between half-dose SS images and DS images reconstructed from one tube only with tube potential of 120 kV or more for phantoms 40 cm or smaller (P < 0.05). For both readers, the patients’ CTC image quality scores were more than 84% concordant between SS or DS CTC images, and half-dose–prone CTC images with SAFIRE had 84% or more concordance with routine-dose CTC except for 3D image noise.

Conclusions: In appropriately sized patients, DS acquisition with single-tube reconstruction can create half-dose images, permitting comparison to full-dose images. For CTC, there is comparable image quality for colonic evaluation between full-dose and half-dose images reconstructed with SAFIRE.

© 2012 Lippincott Williams & Wilkins, Inc.



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