Skip Navigation LinksHome > July/August 2012 - Volume 36 - Issue 4 > Multidetector-Row Computed Tomography Enterographic Assessme...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e31825b878c
Abdominal Imaging

Multidetector-Row Computed Tomography Enterographic Assessment of the Ileal-Anal Pouch: Descriptive Radiologic Analysis With Endoscopic and Pathologic Correlation

Liszewski, Mark C. MD*; Sahni, V. Anik MD*; Shyn, Paul B. MD*; Friedman, Sonia MD; Hornick, Jason L. MD; Erturk, Sukru M. MD*; Mortele, Koenraad J. MD§

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Abstract

Objective: To describe the multidetector-row computed tomography enterographic (MD-CTE) features of the ileal-anal pouch after ileal pouch anal anastomosis (IPAA) surgery and correlate them with pouch endoscopy and histopathologic findings.

Methods: All MD-CTE examinations performed on patients who underwent IPAA from July 1, 2005 to December 1, 2010 (n = 35; 16 [45.7%] men; mean age, 37.7 years; age range, 22–72 years) were retrospectively evaluated in consensus by 2 radiologists. All studies were evaluated for the presence of multiple imaging features. Two radiographic scores were then calculated: a total radiographic score and a radiographic active inflammation score. In patients who underwent MD-CTE, pouch endoscopy, and biopsy within 30 days (n = 13), both scores were correlated with findings on pouch endoscopy and histopathology.

Results: Of the 35 patients, 33 (94%) had at least one MD-CTE finding of active or chronic pouch inflammation and 27 patients (77%) had at least one MD-CTE finding of active pouch inflammation. Of the 13 patients who underwent endoscopy and biopsy, the total radiographic score demonstrated a strong positive correlation with endoscopic score (r = 0.81; P = 0.001) and a moderate positive correlation with histopathologic score (r = 0.56; P = 0.047). The radiographic active inflammation score demonstrated a strong positive correlation with endoscopic score (r = 0.83; P = 0.0004), but only a weak nonsignificant positive correlation with histopathologic score (r = 0.492, P = 0.087).

Conclusions: In patients who had IPAA surgery, findings on MD-CTE correlate positively with findings on pouch endoscopy and histopathology and are sensitive measures for pouch inflammation with high positive predictive value. Thus, MD-CTE can be a useful noninvasive test in the early evaluation of symptomatic patients.

© 2012 Lippincott Williams & Wilkins, Inc.

  

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