Skip Navigation LinksHome > May/June 2012 - Volume 36 - Issue 3 > Computed Tomography Findings of Influenza A (H1N1) Pneumonia...
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Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e31825588e6
Cardiothoracic Imaging

Computed Tomography Findings of Influenza A (H1N1) Pneumonia in Adults: Pattern Analysis and Prognostic Comparisons

Kang, Hee MD*; Lee, Kyung Soo MD*; Jeong, Yeon Joo MD; Lee, Ho Yun MD*; Kim, Kun Il MD; Nam, Kyung Jin MD

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Aim: The aim of this study was to evaluate retrospectively the chest computed tomography findings of influenza A (H1N1) pneumonia and their relationship with clinical outcome.

Methods: Chest computed tomography findings and clinical outcomes of 76 patients with influenza A (H1N1) pneumonia were assessed. Computed tomography findings were evaluated for the presence and distribution of parenchymal abnormalities, which were then classified into 3 patterns: bronchopneumonia, cryptogenic organizing pneumonia (COP), and acute interstitial pneumonia (AIP) patterns. Clinical courses were divided into 2 groups on the basis of necessitating admission to intensive care unit or mechanical ventilation therapy (group 1) or not (group 2).

Results: Lung abnormalities consisted of ground-glass opacity (93%, 71 patients), consolidation (66%, 50 patients), small nodules (61%, 46 patients), and tree-in-bud sign (22%, 17 patients). Lesions were classified into bronchopneumonia (49%, 37 patients), COP (30%, 23 patients), AIP (18%, 14 patients), and unclassifiable (3%, 2 patients) patterns. Patients with AIP pattern had a tendency to belonging to group 1, accounting for 40% (8 of 20 patients) of group 1 course and only 11% (6 of 56 patients) of group 2 course (P = 0.004).

Conclusions: Computed tomography findings of influenza A (H1N1) pneumonia in adults can be classified into COP, AIP, and bronchopneumonia patterns. Patients presenting with AIP pattern have a tendency to show poor prognosis.

© 2012 Lippincott Williams & Wilkins, Inc.



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