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Variation in Hepatic Segmental Volume Distribution According to Different Causes of Liver Cirrhosis: CT Volumetric Evaluation

Kim, In MD; Jang, Yun-Jin MD; Ryeom, Hunkyu MD; Lee, So Mi MD; Lee, Hui Joong MD; Kim, Gab Chul MD; Kim, Hye Jung MD

Journal of Computer Assisted Tomography: March/April 2012 - Volume 36 - Issue 2 - p 220–225
doi: 10.1097/RCT.0b013e31824afd86
Abdominal Imaging

Objective: To investigate if there is difference in hepatic segmental volume distribution according to causes of liver cirrhosis (LC) using computed tomography volumetric analysis.

Methods: On computed tomographic scans, hepatic segmental volumes were measured in 90 patients with LC of 4 different causes (alcohol, hepatitis B virus (HBV), hepatitis C virus (HCV), and cryptogenic cirrhosis). The volumetric indices were compared.

Results: The volume proportion of the lateral segment in the liver in patients with HBV was significantly higher than in the patients with HCV (P = 0.038). Hepatic volume distribution in alcoholic LC showed differences: larger caudate lobe volume than HBV- and HCV-induced LC (P = 0.029 and P = 0.031), larger right lobe volume (P = 0.043) and smaller proportion of the lateral segment in the liver (P = 0.003) than in HBV-induced LC.

Conclusions: Computed tomography volumetric analysis showed differences in hepatic segmental volume distribution in cirrhotic patients according to causes of LC.

From the Department of Radiology, Kyungpook National University Hospital, Jung-Gu, Daegu, Republic of Korea.

Received for publication December 3, 2011; accepted January 12, 2012.

Reprints: Yun-Jin Jang, MD, Department of Radiology, Kyungpook National University Hospital, 200 Dongduk-Ro, Jung-Gu, Daegu 700–721, Republic of Korea (e-mail: yjjang@knu.ac.kr).

The authors report no conflicts of interest.

Copyright © 2012 Wolters Kluwer Health, Inc. All rights reserved.