Skip Navigation LinksHome > November/December 2011 - Volume 35 - Issue 6 > Computed Tomography and Magnetic Resonance Features of Glios...
Text sizing:
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182331128
Original Article

Computed Tomography and Magnetic Resonance Features of Gliosarcoma: A Study of 54 Cases

Zhang, Bi-Yun MM*; Chen, Hong MD; Geng, Dao-Ying MD*; Yin, Bo MD*; Li, Yu-Xin MD*; Zhong, Ping MD; Wu, Jin-Song MD; Wang, Xiao-Qiang PhD*

Collapse Box


Objective: To investigate the features of pathologically confirmed gliosarcomas using computed tomography (CT) and magnetic resonance (MR) imaging.

Methods: We retrospectively reviewed the cross-sectional CT and MR images of 54 patients (37 males and 17 females; mean age, 44.5 years; range, 13–74 years) with gliosarcomas confirmed by histopathology.

Results: Across all patients, there were 59 lesions. On nonenhanced CT and MR images, tumors were predominantly inhomogeneous. On the postcontrast CT and MR images, 50 (84.7%) irregular lesions had thick walls with a strong rim- and ringlike enhancement, whereas the remaining 9 (15.3%) round or oval lesions had even thin walls with an enhanced peripheral ring. Magnetic resonance spectroscopy showed increased choline and lactate values, along with decreased N-acetylaspartate and creatine values. On diffusion-weighted imaging, the tumor was slightly or markedly hyperintense compared with the white matter.

Conclusion: A well-demarcated mass located peripherally, with rimlike or ring enhancement, is a common presentation of gliosarcoma on CT and MR images. In addition, magnetic resonance spectroscopy and diffusion-weighted imaging can be used to make a differential diagnosis.

© 2011 Lippincott Williams & Wilkins, Inc.



Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.