Aim: To compare high-resolution pelvic magnetic resonance imaging (MRI) with positron emission tomography (PET)/computed tomography (CT) for the preoperative assessment of nodal staging in rectal cancer.
Materials and Methods: Thirty patients who had surgery for rectal cancer were retrospectively enrolled during a 6-month period. Each patient underwent high-resolution pelvic MRI and PET/CT preoperatively within the same week. An experienced radiologist predicted nodal staging on MR, and an experienced nuclear medicine physician similarly predicted nodal staging on PET/CT. Their predictions were compared with pathologic staging results, retrospectively.
Results: The accuracies of nodal status prediction from MR and PET/CT were 83% and 70%, respectively. Magnetic resonance imaging had a sensitivity of 94% and a specificity of 67%, whereas PET/CT had a sensitivity of 61% and a specificity of 83%. A combination of MRI and PET/CT revealed a sensitivity of 94%, a specificity of 83%, and an accuracy of 90%.
Conclusion: High-resolution pelvic MRI was more accurate than PET/CT for the prediction of regional nodal status. Magnetic resonance imaging had a high sensitivity and PET/CT had a high specificity for N staging in rectal cancer.
From the *Department of Radiology, Gangnam Severance Hospital, Yonsei University College or Medicine, Seoul; †Department of Radiology, CHA Bundang Medical Center, CHA University, Sungnam; and ‡Department of Nuclear Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Received for publication February 19, 2011; accepted May 20, 2011.
Reprints: Joo Hee Kim, MD, Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 612 Eonjuro, Gangnam-gu, Seoul, Korea (e-mail: firstname.lastname@example.org).
This work was supported by a faculty research grant of Yonsei University College of Medicine for 2008(6-2008-0155)
The authors report no conflicts of interest.