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Nodal Staging of Rectal Cancer: High-Resolution Pelvic MRI Versus 18F-FDGPET/CT

Kim, Dae Jung MD; Kim, Joo Hee MD; Ryu, Young Hoon MD; Jeon, Tae Joo MD; Yu, Jeong-Sik MD; Chung, Jae-Joon MD

Journal of Computer Assisted Tomography: September/October 2011 - Volume 35 - Issue 5 - pp 531-534
doi: 10.1097/RCT.0b013e318225720f
Abdominal Imaging

Aim: To compare high-resolution pelvic magnetic resonance imaging (MRI) with positron emission tomography (PET)/computed tomography (CT) for the preoperative assessment of nodal staging in rectal cancer.

Materials and Methods: Thirty patients who had surgery for rectal cancer were retrospectively enrolled during a 6-month period. Each patient underwent high-resolution pelvic MRI and PET/CT preoperatively within the same week. An experienced radiologist predicted nodal staging on MR, and an experienced nuclear medicine physician similarly predicted nodal staging on PET/CT. Their predictions were compared with pathologic staging results, retrospectively.

Results: The accuracies of nodal status prediction from MR and PET/CT were 83% and 70%, respectively. Magnetic resonance imaging had a sensitivity of 94% and a specificity of 67%, whereas PET/CT had a sensitivity of 61% and a specificity of 83%. A combination of MRI and PET/CT revealed a sensitivity of 94%, a specificity of 83%, and an accuracy of 90%.

Conclusion: High-resolution pelvic MRI was more accurate than PET/CT for the prediction of regional nodal status. Magnetic resonance imaging had a high sensitivity and PET/CT had a high specificity for N staging in rectal cancer.

From the *Department of Radiology, Gangnam Severance Hospital, Yonsei University College or Medicine, Seoul; †Department of Radiology, CHA Bundang Medical Center, CHA University, Sungnam; and ‡Department of Nuclear Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Received for publication February 19, 2011; accepted May 20, 2011.

Reprints: Joo Hee Kim, MD, Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 612 Eonjuro, Gangnam-gu, Seoul, Korea (e-mail: pavane@yuhs.ac).

This work was supported by a faculty research grant of Yonsei University College of Medicine for 2008(6-2008-0155)

The authors report no conflicts of interest.

Copyright © 2011 Wolters Kluwer Health, Inc. All rights reserved.