Skip Navigation LinksHome > July/August 2011 - Volume 35 - Issue 4 > Evaluation of a Continuous-Rotation, High-Speed Scanning Pro...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e31821c662b
Muscoloskeletal Imaging

Evaluation of a Continuous-Rotation, High-Speed Scanning Protocol for Micro-Computed Tomography

Kerl, Hans Ulrich MD; Isaza, Cristina T.; Boll, Hanne MVD; Schambach, Sebastian J. MD; Nolte, Ingo S. MD; Groden, Christoph MD; Brockmann, Marc A. MD, MSc

Collapse Box

Abstract

Objective: Micro-computed tomography is used frequently in preclinical in vivo research. Limiting factors are radiation dose and long scan times. The purpose of the study was to compare a standard step-and-shoot to a continuous-rotation, high-speed scanning protocol.

Methods: Micro-computed tomography of a lead grid phantom and a rat femur was performed using a step-and-shoot and a continuous-rotation protocol. Detail discriminability and image quality were assessed by 3 radiologists. The signal-to-noise ratio and the modulation transfer function were calculated, and volumetric analyses of the femur were performed. The radiation dose of the scan protocols was measured using thermoluminescence dosimeters.

Results: The 40-second continuous-rotation protocol allowed a detail discriminability comparable to the step-and-shoot protocol at significantly lower radiation doses. No marked differences in volumetric or qualitative analyses were observed.

Conclusions: Continuous-rotation micro-computed tomography significantly reduces scanning time and radiation dose without relevantly reducing image quality compared with a normal step-and-shoot protocol.

Copyright © 2011 Wolters Kluwer Health, Inc. All rights reserved.

  

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.