Skip Navigation LinksHome > May/June 2011 - Volume 35 - Issue 3 > Role of Whole-Body Staging Computed Tomographic Scans for De...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e318214ad58
Whole Body Imaging

Role of Whole-Body Staging Computed Tomographic Scans for Detecting Distant Metastases in Patients With Bladder Cancer

Rajesh, Arumugam MBBS, FRCR*; Sokhi, Heminder FRCR*; Fung, Rachael MBBS, BSc*; Mulcahy, Kevin A. FRCR*; Bankart, Michael J.G.†

Collapse Box


Objective: This study aimed to establish the incidence of distant metastases on whole-body computed tomographic (CT) scans in patients with newly diagnosed bladder cancer and to determine whether there is a significant difference in the incidence of metastases in patients with superficial and muscle invasive cancers.

Materials and Methods: A total of 201 patients who had a proven histological diagnosis of transitional cell carcinoma of the bladder and a whole-body staging CT scan at diagnosis were identified from our MDT database during a 36-month period. Imaging was retrospectively reviewed with view to recording site, if any, of distant metastases.

Results: Of 201 patients, 11 (5.5%) were found to have distant metastases on CT. In univariable models, staging was not associated with either age (odds ratio, 0.98; 95% confidence interval, 0.92-1.04; P = 0.4) or sex (Fisher exact test, P = 0.07). Mean (SD) age was 74.1 (10.5) years. There was a significant association between staging and metastasis (odds ratio, 19.9; 95% confidence interval, 3.2-infinity; P = 0.0003). Of the patients, 7% of males had metastases versus 0% of the females.

Conclusions: Staging CT scans for assessment of distant metastatic disease in patients with newly diagnosed bladder cancer can be restricted to patients with muscle invasive disease.

© 2011 Lippincott Williams & Wilkins, Inc.



Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.