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Hepatocellular Adenomas: Current Update on Genetics, Taxonomy, and Management

Shanbhogue, Alampady MD*; Shah, Shetal N. MD†; Zaheer, Atif MD‡; Prasad, Srinivasa R. MD*; Takahashi, Naoki MD§; Vikram, Raghunandan MBBS∥

Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e31820bad61
Abdominal Imaging

Hepatocellular adenomas (HCAs) are uncommon, benign hepatocellular neoplasms that commonly occur in young women. Recent advances in pathology and cytogenetics have thrown fresh light on the pathogenesis of HCAs leading to classification of HCAs into 3 distinct subtypes, each with a characteristic epidemiology, histopathology, oncogenesis, and imaging findings. The aim of the article was to provide a comprehensive review of contemporary taxonomy of HCAs, with an emphasis on cross-sectional imaging findings and management.

Author Information

From the *Departments of Radiology, University of Texas Health Science Center at San Antonio, TX; †Cleveland Clinic, OH; ‡Johns Hopkins University, Baltimore, MD; §Mayo Clinic, Rochester, MN; and ∥University of Texas MD Anderson, Houston, TX.

Received for publication October 22, 2010; accepted December 15, 2010.

Reprints: Srinivasa R. Prasad, MD, Radiology Department, University of Texas HSC at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229 (e-mail:

© 2011 Lippincott Williams & Wilkins, Inc.