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Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3182032537
Abdominal Imaging

Feasibility of Simultaneous Computed Tomographic Colonography and Fully Automated Bone Mineral Densitometry in a Single Examination

Summers, Ronald M. MD, PhD*; Baecher, Nicolai MD*; Yao, Jianhua PhD*; Liu, Jiamin PhD*; Pickhardt, Perry J. MD†; Choi, J. Richard ScD, MD‡; Hill, Suvimol MD*

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Purpose: To show the feasibility of calculating the bone mineral density (BMD) from computed tomographic colonography (CTC) scans using fully automated software.

Materials and Methods: Automated BMD measurement software was developed that measures the BMD of the first and second lumbar vertebrae on computed tomography and calculates the mean of the 2 values to provide a per patient BMD estimate. The software was validated in a reference population of 17 consecutive women who underwent quantitative computed tomography and in a population of 475 women from a consecutive series of asymptomatic patients enrolled in a CTC screening trial conducted at 3 medical centers.

Results: The mean (SD) BMD was 133.6 (34.6) mg/mL (95% confidence interval, 130.5-136.7; n = 475). In women aged 42 to 60 years (n = 316) and 61 to 79 years (n = 159), the mean (SD) BMDs were 143.1 (33.5) and 114.7 (28.3) mg/mL, respectively (P < 0.0001). Fully automated BMD measurements were reproducible for a given patient with 95% limits of agreement of −9.79 to 8.46 mg/mL for the mean difference between paired assessments on supine and prone CTC.

Conclusions: Osteoporosis screening can be performed simultaneously with screening for colorectal polyps.

© 2011 Lippincott Williams & Wilkins, Inc.



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