Skip Navigation LinksHome > November/December 2010 - Volume 34 - Issue 6 > Magnetic Resonance Dynamic Susceptibility-Weighted Contrast-...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3181ef77e2
Neuroradiology

Magnetic Resonance Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion Imaging in the Diagnosis of Posterior Fossa Hemangioblastomas and Pilocytic Astrocytomas: Initial Results

Kumar, Vinodh A. MD; Knopp, Edmond A. MD; Zagzag, David MD, PhD

Collapse Box

Abstract

Objective: The purpose of this study was to compare the dynamic susceptibility-weighted contrast-enhanced (DSC) magnetic resonance (MR) perfusion and MR imaging findings between hemangioblastomas and pilocytic astrocytoma (PA).

Methods: We retrospectively identified 6 patients with hemangioblastomas and 8 patients with PAs who underwent MR imaging before resection. Using fluid-attenuated inversion-recovery imaging, we graded peritumoral edema as absent, minimal, mild, moderate, or severe. In addition, 3 patients with hemangioblastomas and 4 patients with PAs underwent DSC-MR imaging before resection.

Results: We observed moderate to severe peritumoral edema in 6 patients with hemangioblastomas and none or minimal peritumoral edema in 8 patients with PAs. The mean relative cerebral blood volume was 7.7 (SD, 1.0) in patients with hemangioblastomas and 1.8 (SD, 1.8) in patients with PAs.

Conclusions: Our preliminary findings demonstrate significantly higher DSC-MR imaging relative cerebral blood volumes in patients with hemangioblastomas when compared with patients with PAs. In addition, moderate to severe peritumoral edema was associated with hemangioblastomas.

Copyright © 2010 Wolters Kluwer Health, Inc. All rights reserved.

  

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.