Skip Navigation LinksHome > September/October 2010 - Volume 34 - Issue 5 > Usefulness of Z-Score Mapping for Quantification of Extent o...
Journal of Computer Assisted Tomography:
doi: 10.1097/RCT.0b013e3181e66473
Neuroradiology

Usefulness of Z-Score Mapping for Quantification of Extent of Hypoattenuation Regions of Hyperacute Stroke in Unenhanced Computed Tomography: Analysis of Radiologists' Performance

Takahashi, Noriyuki PhD*; Tsai, Du-Yih PhD*; Lee, Yongbum PhD*; Kinoshita, Toshibumi MD, PhD†; Ishii, Kiyoshi MD‡; Tamura, Hajime MD, PhD§; Takahashi, Shoki MD, PhD∥

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Abstract

Objective: The purpose of this study was to evaluate the usefulness of z-score mapping method on neuroradiologists' performance in quantification of the extent of hypoattenuation regions of hyperacute stroke on unenhanced computed tomographic (CT) images by using the Alberta Stroke Programme Early CT Score system.

Methods: Twenty-one patients with infarction (<3 hours) were retrospectively selected. Five neuroradiologists interpreted CT images first without and then with z-score maps by using the Alberta Stroke Programme Early CT Score system. Their performances in the quantification of the extent of hypoattenuation were compared.

Results: Average accuracies for the quantification without and with the z-score maps were 82.6% and 86.6%, respectively (P < 0.0001). The average area under the receiver operating characteristic curve for detection of focal hypoattenuation significantly increased from 0.883 to 0.925 (P = 0.01) by use of z-score maps.

Conclusions: The use of z-score mapping method has the potential to help neuroradiologists quantify the extent of hypoattenuation regions of hyperacute stroke on unenhanced CT images.

© 2010 Lippincott Williams & Wilkins, Inc.

  

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