Skip Navigation LinksHome > January/February 2008 - Volume 32 - Issue 1 > Abdominal Manifestations of Neurofibromatosis
Journal of Computer Assisted Tomography:
doi: 10.1097/rct.0b013e318054e1ca
Abdominal Imaging: Review Article

Abdominal Manifestations of Neurofibromatosis

Hartley, Nicola MBChB, MRCS*; Rajesh, Arumugam MBBS, FRCR*; Verma, Ratan MRCP, FRCR†; Sinha, Rakesh FRCR*; Sandrasegaran, Kumaresan MD‡

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The purpose of this review is to illustrate, with examples, the abdominal manifestations of neurofibromatosis type 1 (NF) on imaging, with emphasis on computed tomography. Mutations of the NF gene lead to abnormal tumor suppression. Consequently, NF is a complex disease, with patients having an increased prevalence of benign and malignant neoplasms throughout the body. We present cases of the most common abdominal presentations: neurofibroma, malignant peripheral nerve sheath tumor, pheochromocytoma, carcinoid, gastrointestinal stromal tumor, and seminoma.

© 2008 Lippincott Williams & Wilkins, Inc.



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