Skip Navigation LinksHome > January/February 2007 - Volume 31 - Issue 1 > Multidetector-Row Computed Tomograpy of Focal Liver Lesions...
Journal of Computer Assisted Tomography:
doi: 10.1097/01.rct.0000232264.36178.1e
Abdominal Imaging: Original Article

Multidetector-Row Computed Tomograpy of Focal Liver Lesions Treated by Radiofrequency Ablation: Spectrum of Findings at Long-term Follow-up

Filippone, Antonella MD; Iezzi, Roberto MD; Di Fabio, Francesca MD; Cianci, Roberta MD; Grassedonio, Emanuele MD; Storto, Maria Luigia MD

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Objective: To assess serial changes in liver tumors after percutaneous radiofrequency ablation at follow-up multidetector-row computed tomography.

Materials and Methods: Forty patients with 65 malignant lesions underwent multidetector-row computed tomography immediately, 1 month and every 3 months, up to a maximum of 15 months after radiofrequency ablation. The computed tomography (CT) appearance of the treated lesions (non-enhanced attenuation, enhancement pattern, shape and size) was assessed at each follow-up. The relationship between each CT finding and the treatment outcome was evaluated by χ2 test (P < 0.05).

Results: No significant differences were found in lesion shape and in non-enhanced CT attenuation between successfully and unsuccessfully treated lesions, whereas over time change of lesion size was significantly different. The no enhancement and nodular enhancement pattern prevalence was significantly (P < 0.0001) different between successfully and unsuccessfully treated lesions, whereas non-nodular enhancement pattern did not show any relationship with the treatment outcome.

Conclusions: Lesion size increase and nodular enhancement pattern resulted significantly related to the treatment failure.

© 2007 Lippincott Williams & Wilkins, Inc.



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