Skip Navigation LinksHome > January/February 2005 - Volume 29 - Issue 1 > Dynamic Subtraction Magnetic Resonance Imaging of Cirrhotic...
Journal of Computer Assisted Tomography:
Original Article: Abdominal Imaging

Dynamic Subtraction Magnetic Resonance Imaging of Cirrhotic Liver: Assessment of High Signal Intensity Lesions on Nonenhanced T1-Weighted Images

Yu, Jeong-Sik MD*†; Kim, Young Hwan MD‡; Rofsky, Neil M MD*

Collapse Box

Abstract

Purpose: The purpose of this work was to determine the technical feasibility and value of dynamic subtraction (postcontrast-precontrast) magnetic resonance (MR) imaging for the assessment of hyperintense lesions on precontrast T1-weighted images in the cirrhotic liver.

Methods: One hundred four hyperintense lesions on T1-weighted precontrast and arterial phase postcontrast images were subjected to analysis of their subtraction qualities depending on the lesion size, location and/or the degree of misregistration between the source images in 27 different MR imaging sets.

Results: The quality of subtraction images was always diagnostic for lesions larger than 2 cm in diameter (n = 8) but not diagnostic for 73% (40 of 55 lesions) of small subcentimetric lesions. Thirty-one subcapsular lesions always showed a variable degree of coregistration artifact. Only 3 of 35 lesions with a slice misregistration of 3 mm or more gave rise to subtraction images of diagnostic quality. For determining the contrast enhancement, the area under the receiver operating characteristic curve of 30 verified lesions was significantly larger (P < 0.001) for subtraction images than for conventional arterial phase images.

Conclusion: Depending on the lesion size and/or location or the degree of misregistration between the source images, dynamic subtraction MR imaging can be useful for the characterization of hyperintense lesions on precontrast T1-weighted imaging.

© 2005 Lippincott Williams & Wilkins, Inc.

  

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.