Skip Navigation LinksHome > May/June 2004 - Volume 28 - Issue 3 > Computed Tomography Colonography: Feasibility of Computer-Ai...
Journal of Computer Assisted Tomography:
Abdominal Imaging

Computed Tomography Colonography: Feasibility of Computer-Aided Polyp Detection in a “First Reader” Paradigm

Mani, Aravind BS*†; Napel, Sandy PHD*; Paik, David S PHD*; Jeffrey, R Brooke Jr MD*; Yee, Judy MD‡§; Olcott, Eric W MD*║; Prokesch, Rupert MD*¶; Davila, Marta MD#; Schraedley-Desmond, Pamela PHD*; Beaulieu, Christopher F MD, PHD*

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Objective: To determine the feasibility of a computer-aided detection (CAD) algorithm as the “first reader” in computed tomography colonography (CTC).

Methods: In phase 1 of a 2-part blind trial, we measured the performance of 3 radiologists reading 41 CTC studies without CAD. In phase 2, readers interpreted the same cases using a CAD list of 30 potential polyps.

Results: Unassisted readers detected, on average, 63% of polyps ≥10 mm in diameter. Using CAD, the sensitivity was 74% (not statistically different). Per-patient analysis showed a trend toward increased sensitivity for polyps ≥10 mm in diameter, from 73% to 90% with CAD (not significant) without decreasing specificity. Computer-aided detection significantly decreased interobserver variability (P = 0.017). Average time to detection of the first polyp decreased significantly with CAD, whereas total reading case reading time was unchanged.

Conclusion: Computer-aided detection as a first reader in CTC was associated with similar per-polyp and per-patient detection sensitivity to unassisted reading. Computer-aided detection decreased interobserver variability and reduced the time required to detect the first polyp.

© 2004 Lippincott Williams & Wilkins, Inc.



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