Skip Navigation LinksHome > May/June 2004 - Volume 28 - Issue 3 > Computed Tomography Colonography: Feasibility of Computer-Ai...
Journal of Computer Assisted Tomography:
Abdominal Imaging

Computed Tomography Colonography: Feasibility of Computer-Aided Polyp Detection in a “First Reader” Paradigm

Mani, Aravind BS*†; Napel, Sandy PHD*; Paik, David S PHD*; Jeffrey, R Brooke Jr MD*; Yee, Judy MD‡§; Olcott, Eric W MD*║; Prokesch, Rupert MD*¶; Davila, Marta MD#; Schraedley-Desmond, Pamela PHD*; Beaulieu, Christopher F MD, PHD*

Collapse Box


Objective: To determine the feasibility of a computer-aided detection (CAD) algorithm as the “first reader” in computed tomography colonography (CTC).

Methods: In phase 1 of a 2-part blind trial, we measured the performance of 3 radiologists reading 41 CTC studies without CAD. In phase 2, readers interpreted the same cases using a CAD list of 30 potential polyps.

Results: Unassisted readers detected, on average, 63% of polyps ≥10 mm in diameter. Using CAD, the sensitivity was 74% (not statistically different). Per-patient analysis showed a trend toward increased sensitivity for polyps ≥10 mm in diameter, from 73% to 90% with CAD (not significant) without decreasing specificity. Computer-aided detection significantly decreased interobserver variability (P = 0.017). Average time to detection of the first polyp decreased significantly with CAD, whereas total reading case reading time was unchanged.

Conclusion: Computer-aided detection as a first reader in CTC was associated with similar per-polyp and per-patient detection sensitivity to unassisted reading. Computer-aided detection decreased interobserver variability and reduced the time required to detect the first polyp.

© 2004 Lippincott Williams & Wilkins, Inc.



Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.