We present a very rare case of parachordoma with local aggressiveness and widespread metastases. A 68-year-old male presented with a mass in his left calf. The lesion was depicted as a poorly marginated mass with inhomogeneous signal intensity on magnetic resonance imaging. The tumor invaded surrounding muscles, neurovascular bundles, and bones. Widespread metastasis to lung, bone, and skin developed after amputation surgery. The histologic features of primary and metastatic lesions were the same and consistent with parachordoma.
From the Departments of Orthopedic Surgery (S. Abe, A. Tateishi, T. Tokizaki, J. Yorikawa, and T. Matsushita), Surgical Pathology (T. Imamura), and Radiology (A. Harasawa), Teikyo University School of Medicine, Tokyo, Japan; Laboratory of Electron Microscopy (K. Unno), Teikyo University School of Medicine, Mizonokuchi Hospital, Tokyo, Japan; and the First Department of Pathology, Tokyo Medical University, Tokyo, Japan (T. Ishida).
Address correspondence and reprint requests to Dr. Satoshi Abe, Department of Orthopedic Surgery, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan. E-mail: firstname.lastname@example.org