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Surgical Management of Metastatic Bone Disease

Bickels, Jacob MD; Dadia, Shlomo MD; Lidar, Zvi MD

Journal of Bone & Joint Surgery - American Volume: 01 June 2009 - Volume 91 - Issue 6 - p 1503–1516
doi: 10.2106/JBJS.H.00175
Current Concepts Review
Supplementary Content

Metastatic bone disease is a major contributor to the deterioration of the quality of life of patients with cancer; it causes pain, impending and actual pathological fractures, and loss of function and may also be associated with considerable metabolic alterations.

Operative treatment may be required for an impending or existing fracture and intractable pain. The goals of surgery are to provide local tumor control and allow immediate weight-bearing and function. Radiation therapy is often indicated postoperatively.

Detailed preoperative evaluation is required to assess the local extent of bone destruction and soft-tissue involvement, involvement of other skeletal sites, and the overall medical and oncological status.

1National Unit of Orthopedic Oncology (J.B. and S.D.) and Spine Care Unit (Z.L.), Tel-Aviv Sourasky Medical Center, 6 Weizmann Street, Tel-Aviv 64239, Israel. E-mail address for J. Bickels:

Copyright 2009 by The Journal of Bone and Joint Surgery, Incorporated
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