Institutional members access full text with Ovid®

Share this article on:

Histological and Alkaline-Phosphatase Changes in Autogenous Transplants of Tibial Grafts in Dogs Treated with Cortisone.

Tonna, Edgar A.; Nicholas, James A.
Journal of Bone & Joint Surgery - American Volume: September 1959
Archive: PDF Only

Cortisone treatment of dogs after transplants of autogenous tibial grafts revealed sharply reduced alkaline-phosphatase activity two and four weeks after surgery. Graft incorporation and suitable trabecular formation were not seen until four weeks after transplantation in corticosteroid-treated dogs; the trabeculae of the callus lacked the usual osteoblastic lining. Histologically and grossly, the graft site in cortisone-treated dogs exhibited a retardation in bone healing of two weeks when compared with that in control dogs.

Copyright 1959 by The Journal of Bone and Joint Surgery, Incorporated

You currently do not have access to this article

To access this article: